Health

Lp(a): The Inherited Cholesterol Behind Early Heart Attacks

Lp(a) is a genetically fixed particle that ~1 in 4 South Asians have at high levels — it doesn't show on a standard lipid profile
Test it ONCE in your life; high is above 50 mg/dL (or 125 nmol/L). Cost in India is roughly ₹600–1500
Statins, diet and exercise barely move Lp(a) — the fix is aggressive control of everything else (LDL, BP, smoking, sugar)
A high reading explains heart attacks in slim, fit, non-smoking people with normal cholesterol
New injectable drugs (pelacarsen, olpasiran) that slash Lp(a) are in late-stage trials, results due soon

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